물리적 외력이 배양중인 치주인대세포에 미치는 영향
The Effects of Mechanical Force on Cultured Periodontal Ligament Cells in Vitro
단국대치의학연구소논문집 1993년 5권 1호 p.295 ~ 302
김현영, 차경석,
소속 상세정보
김현영 ( ) - 단국대 치의학연구소
차경석 ( Cha Kyung-Suk ) - 단국대 치의학연구소
KMID : 0354619930050010295
Abstract
The movement of teeth during orthodontic treatment requires bone remodeling process in periodontal tissue.
To find out the changes occuring in the cell itself, mechanical force was applied to the cultured peridontal ligament cells.
Following results were obtained from measuring the changes in cyclic AMP and PGE2, 3H-thymidine incorporation amount in time lapse after application of mechanical force.
1. When mechanical force was applied to cultured PDL cells, the amount of cAMP in cells were increased significantly after 15 min, of force application, but were decreased gradually as time lapsed.
2. When mechanical force was applied to cultured PDL cells, the amount of PGE2 were increased at 20, 40, 50 min. and was significantly increased at 20 min.
3. When mechanical force was applied to cultured PDL cells, the amount of 3H-thymidine incorporation was some increased, but was not statistically significant.
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